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TROPION-Lung01: Datopotamab Deruxtecan (Dato-DXd) in Combination With Docetaxel (DTX) in Patients With Advanced Nonsquamous NSCLC With Brain Metastases
ESMO 2024 - Wrap-Up: Non-Small Cell Lung Cancer
The TROPION-Lung01 trial found a significant improvement in progression-free survival when comparing Dato-DXd to DTX in patients with advanced non-small cell lung cancer (NSCLC), particularly those with nonsquamous histology.
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Wrap-Up
GFPC 03-2019: A Comprehensive National Analysis of the Management of Patients With ROS1-Positive Metastatic NSCLC
ESMO 2024 - Wrap-Up: Non-Small Cell Lung Cancer
The Explore ALK/ROS study investigated the management practices and clinical outcomes of patients with advanced non-small cell lung cancer (NSCLC) who tested positive for
ROS1
.
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Wrap-Up
Comprehensive Genomic Profiling Enables Patients to Access Innovative Matched Therapies Within a Varied Real-World Cohort of Patients Suffering From Advanced Lung Cancer
ESMO 2024 - Wrap-Up: Non-Small Cell Lung Cancer
A retrospective analysis was performed on deidentified records of patients with metastatic non-small cell lung cancer to assess adherence with the targeted therapy recommendations outlined in the ESMO and NCCN guidelines and to analyze the duration from genomic sequencing to the commencement of targeted treatment.
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Wrap-Up
Phase 2 Study Evaluating the Safety and Efficacy of Pembrolizumab, Plinabulin, and Docetaxel in Patients With Metastatic NSCLC After Failure on First-Line Immune Checkpoint Inhibitors
ESMO 2024 - Wrap-Up: Non-Small Cell Lung Cancer
This phase 2 study aimed to assess the efficacy and safety of a combination of pembrolizumab, plinabulin, and docetaxel in patients with metastatic non-small cell lung cancer (NSCLC) who have developed resistance to immunotherapy.
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BEAT-SC Trial: Phase 3 Study of Bevacizumab or Placebo With Atezolizumab and Platinum-Based Chemotherapy in ES-SCLC
ESMO 2024 - Small Cell Lung Cancer
The second interim analysis of overall survival from the BEAT-SC trial assessed bevacizumab for its effectiveness and safety in combination with atezolizumab and platinum-based chemotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC) in Japan and China.
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Real-World Outcomes of Relapsed and Refractory Systemic Therapy in the Canadian SCLC Database (CASCADE)
ESMO 2024 - Small Cell Lung Cancer
This study evaluated real-world treatments and outcomes of limited disease small cell lung cancer (SCLC) using the Canadian SCLC Database (CASCADE).
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An Open-Label, Multicenter Phase 2 Trial Assessed Encorafenib Plus Binimetinib in Patients With Previously Untreated BRAF V600E-Mutant Advanced NSCLC
ESMO 2024 - Small Cell Lung Cancer
An ongoing, open-label, single-arm phase 2 study (IFCT-1904) evaluated patients with untreated
BRAF
V600E-mutant non-small cell lung cancer (NSCLC) who received encorafenib plus binimetinib.
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Results of a Phase 2 Study Evaluating Lurbinectedin and Irinotecan in Relapsed SCLC Patients With Chemotherapy-Free Interval >30 Days
ESMO 2024 - Small Cell Lung Cancer
Data from phase 2 trials involving lurbinectedin and irinotecan have been analyzed for patients with relapsed small cell lung cancer (SCLC) who have had a chemotherapy-free interval of >30 days.
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Analysis of 5-Year Outcomes From the NEOSTAR and CA209-159 Studies on Neoadjuvant Nivolumab and the Combination of Nivolumab With Ipilimumab in Resectable NSCLC
ESMO 2024 - Small Cell Lung Cancer
A pooled analysis of 5-year clinical outcomes from 2 early-phase trials, NEOSTAR and CA209-159, showed promising long-term clinical effectiveness in patients with resectable non-small cell lung cancer (NSCLC).
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Wrap-Up
COMMANDS Trial in Transfusion-Dependent, Erythropoiesis-Stimulating Agent–Naïve Patients With Very Low-, Low-, or Intermediate-Risk MDS: Multilineage and Safety Results
EHA 2024 - Wrap-Up: Myelodysplastic Syndrome
At the 2024 European Hematology Association Annual Congress, researchers presented the multilineage and safety results from the COMMANDS trial of transfusion-dependent, erythropoiesis-stimulating agent–naïve patients with very low-, low-, or intermediate-risk myelodysplastic syndromes.
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