Articles

Results of the phase 2 CLL2-BAAG trial showed that MRD-guided triple combination therapy of acalabrutinib, venetoclax and obinutuzumab yielded better efficacy outcomes, deeper remission, and achievement of uMRD in patients with R/R CLL. Read More ›

Data from an ongoing, first-in-human phase 1/2 study suggests that combination sonrotoclax (160 mg and 320 mg) plus zanubrutinib therapy was well tolerated and showed encouraging anti-leukemic activity in patients with treatment-naive CLL/SLL. Read More ›

Retrospective study of patients with HR+/HER2− metastatic breast cancer with bone-only metastases and pre-clinical data finds CDK4/6 inhibitors not as effective as in patients with metastases to other body sites. Read More ›

The development of action plans by providers and use of educational sessions found to improve patient compliance with oral oncolytics for those with HR+/HER2− breast cancer. Read More ›

Real-world analysis finds a preference shift from palbociclib to ribociclib and no significant differences in time to next treatment or time to treatment discontinuation for patients with HR+/HER-metastatic breast cancer. Read More ›

Study finds that patients with ER+/HER2− metastatic breast cancer who have prior CDK4/6 inhibitor treatment have a greater PFS when treated with elacestrant compared to standard of care. Read More ›

Oncology nurse navigators who work with younger patients with breast cancer and patients with metastatic breast cancer report barriers to services, information, and referrals. Read More ›

The phase 3 HER2CLIMB-02 trial demonstrated significant prolongation of progression-free survival with tucatinib plus ado-trastuzumab emtansine combination therapy in patients with previously treated HER2+ metastatic breast cancer (MBC). Read More ›

This correlative study identified significant differences in the expression of estrogen receptor between tumor tissue and circulating tumor cell analyses in metastatic breast cancer (MBC). Read More ›

In a prospective HER2+ metastatic breast cancer (MBC) cohort, one-third of patients achieved exceptional response to first-line HER2-targeted therapy, who presented more frequently with de novo disease and HER2 immunohistochemistry 3+ tumors. Read More ›