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Transfusion-Dependent Patients With Lower-Risk MDS Receiving Luspatercept or Epoetin Alfa: Hb and QOL
EHA 2024 - Wrap-Up: Myelodysplastic Syndrome
At the European Hematology Association 2024 Annual Conference, researchers analyzed the relationship between hemoglobin and the quality of life of transfusion-dependent patients with lower-risk myelodysplastic syndromes receiving luspatercept or epoetin alfa.
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Luspatercept in Clinical Practice: Real-World Dose Escalation and Outcomes Among Patients With Lower-Risk MDS Receiving Luspatercept in Clinical Practice
EHA 2024 - Wrap-Up: Myelodysplastic Syndrome
At the European Hematology Association 2024 Annual Conference, researchers presented the real-world dose escalation of luspatercept and its outcomes among patients with lower-risk myelodysplastic syndromes.
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Transfusion-Dependent Lower-Risk MDS: The Humanistic and Economic Burden on Patients in North America and Europe
EHA 2024 - Wrap-Up: Myelodysplastic Syndrome
At the European Hematology Association 2024 Annual Conference, researchers explored the emotional, physical, and financial burden experienced by patients with transfusion-dependent lower-risk myelodysplastic syndromes based in North America and Europe.
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Lower-Risk MDS: The Value of Early Luspatercept Use
EHA 2024 - Wrap-Up: Myelodysplastic Syndrome
Researchers presented a model to compare treatment outcomes for patients with lower-risk myelodysplastic syndromes who rely on red blood cell transfusions starting from first-line treatment initiation throughout their lifetime.
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MDS/Neoplasms: Time Toxicity for Patients Receiving Oral Versus Parenteral HMAs
ASCO 2024 - Wrap Up: Myelodysplastic Syndrome
At the ASCO 2024 Annual Meeting, researchers presented the differences in time toxicity among patients undergoing myelodysplastic syndromes/neoplasms with oral hypomethylating versus parenteral hypomethylating agents.
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Phase 2 Results From the ASTREON Trial: Preliminary Safety and Efficacy of Oral AZA in Patients With Low-/Intermediate-Risk MDS
ASCO 2024 - Wrap Up: Myelodysplastic Syndrome
At the ASCO 2024 Annual Meeting, researchers presented oral azacitidine’s safety and efficacy results in patients with low-/intermediate-risk myelodysplastic syndromes, as documented in the ASTREON trial.
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Latest Results of a Phase 2 Study of IMM01 Combined With AZA: First-Line Treatment in Adults With HRMDS
ASCO 2024 - Wrap Up: Myelodysplastic Syndrome
At the ASCO 2024 Annual Meeting, researchers summarized the most recent results from the phase 2 study of IMM01 in combination with azacitidine, a first-line treatment for adults with higher-risk myelodysplastic syndromes.
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Efficacy of Luspatercept for the Treatment of Transfusion-Dependent, Erythropoiesis-Stimulating Agent–Naïve Patients With Very Low-, Low-, or Intermediate-Risk MDS in the COMMANDS Trial
ASCO 2024 - Wrap Up: Myelodysplastic Syndrome
At the 2024 ASCO Annual Meeting, researchers’ data from the COMMANDS trial, which evaluated the effectiveness of luspatercept in treating patients with transfusion-dependent, erythropoiesis-stimulating agent–naïve individuals with very low-, low-, or intermediate-risk myelodysplastic syndromes.
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MRD-Guided Zanubrutinib, Venetoclax and Obinutuzumab Maintenance in Relapsed/Refractory CLL
ASH 2023 - CLL
Results of the phase 2 CLL2-BZAG trial indicated that MRD-guided triple combination of zanubrutinib, venetoclax, and obinutuzumab induced deep remissions in patients with R/R CLL including those previously treated with BTKi and/or venetoclax.
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Response to Subsequent Novel Therapies and Time to Second Progression-Free Survival Event in the MURANO Trial in Patients with R/R CLL Previously Treated with Fixed-Dose Venetoclax/Rituximab
ASH 2023 - CLL
Final data from the phase 3 MURANO trial demonstrated a significantly prolonged time to second progression-free survival event in the venetoclax/rituximab arm, with high response rates achieved even by patients who subsequently received retreatment or crossed over to venetoclax-based regimens or BTKi therapy.
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