Articles

Importance of Health Equity in Gynecologic Cancers
In this second installment, Paula will discuss a health equity study investigating the association of neighborhood socioeconomic deprivation in patients with gynecologic cancers. Read More ›

SIM0270 Monotherapy and in Combination With Everolimus Shows Promise in Advanced Breast Cancer Treatment
Dr Erica Mayer explains the results of a study utilizing the novel SERD SIM0270, as monotherapy and in combination, in the treatment of patients with estrogen receptor–positive, HER2-negative advanced breast cancer. Read More ›

Study Demonstrates Elacestrant Benefit Is Maintained Regardless of ESR1 Mutation Levels
Dr Erica Mayer discusses an analysis of the EMERALD study, which explores the effects of variant allele frequencies on outcomes for patients with advanced breast cancer being treated with elacestrant. Read More ›

Real-World Outcomes of Elacestrant in Patients With ESR1-Mutated Breast Cancer
Dr Erica Mayer comments on real-world outcomes for elacestrant derived from the GuardantINFORM database, and describes which patients elacestrant therapy may be best for. Read More ›

Imlunestrant Shows Promise for Patients With ESR1-Mutated Advanced Breast Cancer
Dr Erica Mayer discusses the positive results of the EMBER-3 trial, and the impact that imlunestrant will have on the treatment of patients with advanced breast cancer Read More ›

SIM0270, a new monotherapy treatment for advanced breast cancer, shows promising clinical activity and a manageable safety profile in a phase 1 clinical trial. Read More ›

SIM0270, a novel selective estrogen receptor degrader, combined with everolimus shows preliminary efficacy with a high rate of treatment-emergent adverse events at the recommended dose in treating patients with advanced breast cancer. Read More ›

Racial disparities are evident in the treatment and outcomes for patients with hormone receptor–positive/HER2-negative metastatic breast cancer in the United States. Read More ›

The ZEST study explored the potential of niraparib in treating early-stage breast cancer patients with detectable ctDNA, paving the way for future research on personalized treatment strategies based on ctDNA detection. Read More ›

Final analysis of the DAWNA-2 trial confirms the addition of dalpiciclib to endocrine therapy significantly improves progression-free survival in patients with hormone receptor–positive/HER2-negative advanced breast cancer. Read More ›

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