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Articles
Articles
Imlunestrant Shows Promise in Treating Advanced Breast Cancer
SABCS 2024 - Breast Cancer
Imlunestrant, a novel oral SERD, demonstrates promising efficacy and safety in a phase 3 trial for advanced breast cancer patients.
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Camizestrant Combination Shows Potential in Treating Advanced Breast Cancer
SABCS 2024 - Breast Cancer
Early results from the SERENA-1 trial show camizestrant combined with ribociclib may be safe and effective for treating estrogen receptor–positive/HER2-negative advanced breast cancer.
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Elacestrant Real-World Outcomes Exceed Expectations
SABCS 2024 - Breast Cancer
A new study shows promising real-world results for elacestrant in advanced breast cancer patients with
ESR1
mutations, exceeding prior clinical trial data.
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Elacestrant Combinations in Advanced Breast Cancer: A Phase 1b Safety and Efficacy Analysis
SABCS 2024 - Breast Cancer
Ongoing trials suggest that combining elacestrant with other therapies may offer a safe and effective treatment option for estrogen receptor–positive/HER2-negative metastatic breast cancer.
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The Evolution of Selective Estrogen Receptor Degraders (SERDs) in Breast Cancer Treatment
SABCS 2024 - Breast Cancer
While SERDs have a storied history, advancements of newer agents like elacestrant and imlunestrant have been successful in overcoming limitations of older treatments
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Liquid Biopsy: A New Era in Breast Cancer Management
SABCS 2024 - Breast Cancer
Liquid biopsy using ctDNA analysis is transforming breast cancer care, offering potential for personalized treatment, early detection, and monitoring response.
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Combination With Endocrine Therapy and Palbociclib Proves Superior for High-Risk Metastatic Breast Cancer
SABCS 2024 - Breast Cancer
The PADMA phase 3 trial demonstrated that combining palbociclib with endocrine therapy significantly outperformed standard chemotherapy in treating high-risk HR-positive/HER2-negative metastatic breast cancer.
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Trastuzumab Deruxtecan Versus Chemotherapy: Efficacy by Disease Progression in DESTINY-Breast06
SABCS 2024 - Breast Cancer
The DESTINY-Breast06 phase 3 trial showed that trastuzumab deruxtecan significantly improved progression-free survival in HR-positive, HER2-low, HER2-ultralow metastatic breast cancer.
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SOLTI VALENTINE: HER3-DXd Alone or With Letrozole in High-Risk HR-Positive/HER2-Negative Early Breast Cancer
SABCS 2024 - Breast Cancer
The SOLTI VALENTINE phase 2 study explored HER3-DXd as a promising treatment for high-risk HR-positive/HER2-negative early breast cancer, showing the therapy’s ability to induce strong immune responses.
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Wrap-Up
Combined Efficacy and Safety Data From 2 Phase 2 Trials of Taletrectinib in Patients Diagnosed With Advanced or Metastatic ROS1-Positive NSCLC
ESMO 2024 - Wrap-Up: Non-Small Cell Lung Cancer
Safety and efficacy data evaluating taletrectinib in patients diagnosed with advanced or metastatic
ROS1
-positive non-small cell lung cancer (NSCLC) were reported from the TRUST-I and TRUST-II phase 2 studies.
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