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Videos
Patient-Reported Outcomes Highlight Favorable Tolerability of Zongertinib in HER2-Mutant NSCLC: Insights From the Beamion LUNG-1 Trial
By
Beth Sandy, MSN, CRNP, FAPO
ASCO 2025 - Non-Small Cell Lung Cancer
Patient-reported outcomes from the Beamion LUNG-1 trial showed sustained improvements in physical functioning and symptom burden, with low side effect severity, supporting zongertinib’s potential in advanced NSCLC.
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Videos
Safety and Efficacy of Sevabertinib (BAY 2927088) in HER2-Mutant Advanced Non-Small Cell Lung Cancer (NSCLC): Results From the Phase I/II SOHO-01 Trial
By
Beth Sandy, MSN, CRNP, FAPO
ASCO 2025 - Non-Small Cell Lung Cancer
The SOHO-01 trial highlights the manageable safety and promising efficacy of sevabertinib (BAY 2927088) in patients with pretreated or untreated HER2-mutant NSCLC.
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Videos
Promising Efficacy and Manageable Safety of Zongertinib in HER2-Mutant NSCLC: Insights From the Beamion LUNG-1 Trial
By
Martin F. Dietrich, MD, PhD
AACR 2025 - Non–Small Cell Lung Cancer
The Beamion LUNG-1 study explored zongertinib as a promising
HER2
-targeted therapy for advanced or metastatic non–small cell lung cancer (NSCLC).
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Videos
Efficacy and Safety of Tiragolumab Plus Atezolizumab in PD-L1–High NSCLC: Insights From the SKYSCRAPER-01 Trial
By
Martin F. Dietrich, MD, PhD
AACR 2025 - Non–Small Cell Lung Cancer
SKYSCRAPER-01 evaluated the combination of tiragolumab and atezolizumab and suggests potential antitumor activity in NSCLC.
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Videos
Safety of Imlunestrant in ER-Positive, HER2-Negative Advanced Breast Cancer: EMBER-3 Trial Results
By
Hope S. Rugo, MD, FASCO
ASCO 2025 - Breast Cancer Faculty Commentary
EMBER-3 trial findings position imlunestrant monotherapy or in combination with abemaciclib as a promising, safe and effective oral therapeutic option for treating estrogen receptor (ER)-positive, HER2-negative advanced breast cancer.
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Videos
Promising Results for Elacestrant Combinations in ER-Positive, HER2-Negative Metastatic Breast Cancer: ELEVATE Trial Findings
By
Hope S. Rugo, MD, FASCO
ASCO 2025 - Breast Cancer Faculty Commentary
Elacestrant in combination with ribociclib or everolimus demonstrates promising efficacy and manageable safety in patients with estrogen receptor (ER)-positive, HER2-negative metastatic breast cancer who experienced disease progression after endocrine therapy plus CDK4/6 inhibitors,
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Videos
SERENA-6 Phase 3 Trial: Camizestrant Plus CDK4/6 Inhibitor for ctDNA-Guided Treatment of ESR1 Mutations in HR-Positive, HER2-Negative Advanced Breast Cancer
By
Hope S. Rugo, MD, FASCO
ASCO 2025 - Breast Cancer Faculty Commentary
The SERENA-6 trial reveals camizestrant's potential to improve outcomes in hormone receptor (HR)-positive, HER2-negative breast cancer by utilizing circulating tumor DNA (ctDNA)-guided therapy towards ESR1 mutations before disease progression.
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Videos
Patient-Reported Outcomes of Imlunestrant in EMBER-3 Trial for ER-Positive, HER2-Negative Advanced Breast Cancer
By
Hope S. Rugo, MD, FASCO
ASCO 2025 - Breast Cancer Faculty Commentary
Patient-reported outcomes from EMBER-3 demonstrate that imlunestrant improves global health status/quality of life and physical function in patients with ESR1 mutations in estrogen receptor (ER)-positive, HER2-negative advanced breast cancer.
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Wrap-Up
Phase 2 Study of BEBT-209 Plus Gemcitabine and Carboplatin in Metastatic TNBC
ASCO 2025 - Wrap-Up: Triple-Negative Breast Cancer
The combination of BEBT-209 with gemcitabine and carboplatin showed promising efficacy and a tolerable safety profile in metastatic triple-negative breast cancer (TNBC).
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Wrap-Up
NeoSTAR Arm A2: Evaluating Sacituzumab Govitecan and Pembrolizumab as Neoadjuvant Therapy for Early-Stage TNBC
ASCO 2025 - Wrap-Up: Triple-Negative Breast Cancer
Sacituzumab govitecan and pembrolizumab combination therapy showed promising clinical benefit in early-stage triple-negative breast cancer (TNBC).
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