The LORETTA trial evaluates tamoxifen monotherapy as a potential nonsurgical option for carefully selected patients with low-risk, estrogen receptor–positive/HER2-negative ductal carcinoma in situ. Watch Video ›

Discover how combining preoperative radiation with immunotherapy is revolutionizing treatment for high-risk, HR-positive/HER2-negative breast cancer in a groundbreaking clinical trial. Watch Video ›

New research reveals that preoperative breast MRI may not improve outcomes for early-stage breast cancer patients, challenging its routine use in surgical planning. Watch Video ›

New insights reveal patient preferences for oral endocrine therapy over intramuscular options in metastatic breast cancer, emphasizing the need for personalized treatment decisions. Watch Video ›

New research highlights critical gaps in ESR1 mutation testing for estrogen receptor (ER)-positive/HER2-negative metastatic breast cancer, emphasizing the need for increased use of blood-based circulating tumor DNA methods to improve treatment outcomes. Watch Video ›

The ADELA trial investigates the potential of combining elacestrant with everolimus to overcome resistance and improve outcomes in ESR1-mutated, estrogen receptor (ER)-positive/HER2-negative advanced breast cancer after progression on endocrine therapy and CDK4/6 inhibitors. Watch Video ›

Discover the latest breakthroughs in breast cancer treatment, as innovative strategies to overcome resistance to CDK inhibitors are explored, and new therapeutic possibilities are unlocked. Watch Video ›

Explore cutting-edge strategies and emerging therapies designed to tackle resistance after CDK4/6 inhibitor progression in advanced breast cancer. Watch Video ›

Discover how oral SERDs and innovative combination therapies are reshaping breast cancer treatment, offering new hope for patients with advanced and resistant disease. Watch Video ›