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American Society of Hematology (ASH)
American Society of Hematology (ASH)
The
American Society of Hematology
(
ASH
) is a professional organization representing hematologists. It was founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medical journal
Blood
, the most cited peer-reviewed publication in the field, which is available weekly in print and online, as well as the newly launched, online, peer-reviewed open-access journal,
Blood Advances
.
Dose-Optimized Nilotinib in Patients with Newly Diagnosed CML-CP: Final Results from ENESTxtnd Study
ASH 2015 – Leukemia
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Understanding the Challenges in Prescribing Oral Oncolytics
ASH 2015 – Multiple Myeloma
R. Donald Harvey conveys his management challenges with patients taking these therapies.
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Bortezomib/Melphalan/Prednisone (VMP) Followed by Lenalidomide/Dexamethasone (Rd) Overcomes the Poor Prognosis of High-Risk Cytogenetics in Elderly Patients with NDMM
ASH 2015 – Multiple Myeloma
Researchers examined subset of elderly newly diagnosed myeloma patients from the GEM2010 trial and split the patients into 2 arms determined by their cytogenetic abnormalities (high risk and standard risk). Patients with 1q gains were shown to have similar outcomes to those without q1 gains when treated with bortezomib plus melphalan and prednisone, followed by lenalidomide and dexamethasone.
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Effect of Nilotinib Treatment Duration on Treatment-Free Remission in CP-CML Patients Previously Treated with Imatinib: Interim Results of the ENESTPath Phase 3 Trial
ASH 2015 – Leukemia
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Multikinase Inhibitor Midostaurin in Newly Diagnosed AML Patients with FLT3 Mutations: Results of the CALGB 10603/RATIFY Trial
ASH 2015 – Leukemia
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Real-World Results of Bortezomib-Based Induction therapy in Newly Diagnosed MM
ASH 2015 – Multiple Myeloma
Researchers demonstrated that any reduction of dose intensity from 1.3 mg/m2 of bortezomib as a first-line treatment for untreated multiple myeloma patients is associated with inferior OS. Furthermore, it was suggested that the cumulative bortezomib dose be ≥20.75 mg for a better OS.
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Clinical Impact of MRD Monitoring in Elderly Patients with MM
ASH 2015 – Multiple Myeloma
The elderly are an important subgroup within multiple myeloma patients, and it is important to continuously monitor MRD to help balance efficacy and toxicity of treatments. Researchers demonstrated that MRD negativity was associated with significant improved survival regardless of age or cytogenetic risk.
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Allogeneic SCT After High versus Reduced-Intensity Conditioning in Patients with MDS or AML: Results of a Phase 3 BMT CTN 0901 Trial
ASH 2015 – Leukemia
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Obinutuzumab plus Ibrutinib as Induction and Maintenance Therapy After Bendamustine Debulking in Patients with CLL: Interim Results of a Phase 2 CLL2-BIG Trial
ASH 2015 – Castleman's Disease, Lymphoma & CLL
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Carfilzomib plus Filanesib versus Carfilzomib in Patients with Advanced Multiple Myeloma
ASH 2015 – Multiple Myeloma
Filanesib, a kinesin spindle protein inhibitor, has demonstrated promising clinical activity in patients with multiple myeloma refractory to proteasome inhibitors and immunomodulatory drugs. This new combination demonstrated good tolerability and an increased observed response rate compared with carfilzomib alone.
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