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American Society of Hematology (ASH)
ASH 2017 – AML
ASH 2017 – AML
Lirilumab plus Azacitidine in Heavily Pretreated, Relapsed AML
ASH 2017 – AML
The results of the current phase 1b/2 study showed that the combination of azacitidine plus lirilumab was well-tolerated in heavily pretreated patients with relapsed acute myeloid leukemia (AML) and poor-risk disease features.
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Continuing Enasidenib Treatment Improves Survival and Responses for Mutant-IDH2 R/R AML Patients with Stable Disease
ASH 2017 – AML
An analysis of response and survival outcomes from the phase 1/2 AG221-C-001 study showed that continued treatment with enasidenib resulted in improved survival and response times in patients with mutant-
IDH2
relapsed or refractory (R/R) acute myeloid leukemia (AML).
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Dual FLT3 and CDK4/6 Inhibition Shows Modest Activity in Relapsed/Refractory AML
ASH 2017 – AML
A phase 1 dose-escalation study of FLX925, a dual FLT3 and CDK4/6 inhibitor, showed modest antileukemic activity in adult patients with relapsed or refractory acute myeloid leukemia (AML).
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Nivolumab plus Azacitidine Shows Encouraging Activity in R/R AML or as Frontline Therapy in Elderly Patients with AML
ASH 2017 – AML
Combination treatment with nivolumab plus azacitidine produced encouraging response rates in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) with poor-risk features, and in elderly patients as frontline therapy.
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