The PD-1 inhibitor nivolumab, in combination with azacytidine, may represent an effective treatment option for some patients with relapsed acute myeloid leukemia (AML).
Patients with acute myeloid leukemia (AML) and TP53 mutations may benefit from certain types of low-intensity chemotherapy.
In a phase 1 study, the mIDH2 inhibitor enasidenib showed promise as a potential emerging therapy for patients with relapsed or refractory acute myeloid leukemia (AML).
Synthetic control arms may represent an efficient, cost-effective way to evaluate early end points in clinical trials.
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