Articles

The US Food and Drug Administration has approved omadacycline for the treatment of adults with community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. Read More ›

A dedicated infectious disease stewardship program can have immediate impact on patient safety, treatment of appropriate disease states, and the reduction of unnecessary readmission to the acute care hospital. Read More ›

Shortening the duration of antimicrobial therapy to that recommended in guidelines may reduce the risk for collateral damage due to Clostridium difficile infection. Read More ›

The researchers assessed the impact of antimicrobial stewardship program interventions in elderly patients on 30-day readmissions due to treatment failure and decreased antibiotic expenditures per adjusted patient-day. Read More ›

A pooled analysis showed favorable safety results from phase 3 studies of omadacycline, a new once-daily intravenous/oral therapy for the monotherapy of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. Read More ›

Pooled safety data of eravacycline in 3 comparator-controlled studies for the treatment of complicated intra-abdominal infections showed that it was generally well-tolerated compared with ertapenem and meropenem. Read More ›

Evaluation of lefamulin, a novel oral antimicrobial, in patients with community-acquired bacterial pneumonia demonstrated noninferiority for both the US Food and Drug Administration and European Medicines Agency efficacy end points versus oral moxifloxacin. Read More ›

In patients with community-acquired pneumonia, a regimen that includes a fluoroquinolone (and possibly a macrolide) may reduce mortality compared with beta-lactams (with or without a beta-lactamase inhibitor) and cephalosporins alone. Read More ›

A protocol to guide rational antibiotic therapy in patients receiving extracorporeal membrane oxygenation can lead to a reduction in the use of specific antibiotics, but paradoxically, may increase overall antibiotic use. Read More ›

Accurate anatomic subtyping, optimal diagnostic imaging, and molecular classification are among the most pressing needs with NETs. Read More ›