Articles

Zanubrutinib is an investigational, next-generation Bruton tyrosine kinase inhibitor. It has been tested in previously untreated patients with del(17p) chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) who are enrolled in the SEQUOIA trial. Read More ›

CAR T-cell therapy – a type of cancer treatment that uses specially altered T-cells from the human body to attack cancer cells – could soon be used to fight multiple myeloma. CAR T-cell therapy has shown huge promise in other types of cancer but would be a new treatment for patients with this type of cancer. Read More ›

An updated analysis of combined or pooled data from studies of ibrutinib. For the first time, a comparison of outcomes with ibrutinib versus patients’ prior treatment regimens for mantle-cell lymphoma is shared. Read More ›

Zanubrutinib is a next-generation Bruton tyrosine kinase inhibitor that has been shown to be potent and selective. Preliminary data suggest durable clinical responses in patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Read More ›

Exciting new research shows that adding daratumumab to a common multiple myeloma treatment slowed down cancer progression in patients who had relapsed or did not respond to other treatments. Read More ›

Preliminary results of the SEQUOIA trial suggested that zanubrutinib was active and generally well tolerated in treatment-naïve patients with del(17p) chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Read More ›

The ongoing phase 1/2 HOVON 124/Ecwm-R2 trial showed the combination of ixazomib citrate, rituximab, and dexamethasone to be feasible, with promising efficacy and manageable toxicity in patients with relapsed or progressive Waldenström macroglobulinemia. Read More ›

Chimeric antigen receptor (CAR) T-cells represent a novel and exciting strategy for patients with blood cancers. This study evaluated lisocabtagene maraleucel, an investigational CAR T-cell product, for patients with relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma. Read More ›

In patients with newly diagnosed multiple myeloma who were fit for transplant, adding daratumumab to a commonly used treatment regimen led to impressive responses. Read More ›

Diffuse large B-cell lymphoma is an aggressive type of non-Hodgkin lymphoma that is particularly difficult to treat if the patient becomes refractory to or relapses after initial treatment. Chances of survival are especially poor for people who are not eligible for stem-cell transplant. Read More ›