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Articles
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Epidemiology
Heterogeneity of Populations and Outcomes for Patients with Relapsed or Refractory DLBCL
AMCP Nexus 2022
Systematic literature review finds substantial variability in patient characteristics and response rates across DLBCL trials
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Economic Burden
Out-of-Pocket Costs Incurred by Patients with Cancer: Findings from a Retrospective Claims Analysis
AMCP Nexus 2022
Medicare Advantage claims analysis explores economic burden of cancer by type and stage, underscoring the importance of early detection
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Drug Coverage and Cost-Effectiveness
Consistency of Specialty Drug Coverage in Payers’ Benefit Designs
AMCP Nexus 2022
Analysis of health plans examines the variability in specialty drug coverage among medical and pharmacy benefit policies
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Patient Engagement and Preference
Good Practices for Patient Involvement When Developing Clinical Practice Guidelines
AMCP Nexus 2022
Analysis of clinical practice guidelines identified 10 good practice recommendations for engaging patients in the development process
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Year in Review
Circulating Tumor DNA–Guided Therapy of Advanced NSCLC with Immune Checkpoint Inhibitor–Based Regimens
NSCLC IO 2022 - Midyear Review
Analysis of circulating tumor DNA can identify patients at high risk of early disease progression who could benefit from combining immune checkpoint inhibitors with chemotherapy.
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Year in Review
Lung Cancer Treatment Selection Based on a Multiplexed Proteomic Assay
NSCLC IO 2022 - Midyear Review
A highly multiplexed proteomic assay was developed to guide treatment selection for patients with lung cancer.
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Year in Review
Machine Learning–Based Integration of Radiology, Pathology, and Genomics to Predict Response to PD-1 Inhibition in Patients with NSCLC
NSCLC IO 2022 - Midyear Review
Implementing a machine learning–based system that integrates radiologic, pathologic, and genomic data to predict response to PD-1 blockade may be able to outperform conventional unimodal approaches.
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Year in Review
Investigation of Acquired Resistance Biomarkers to Anti–PD-(L)1 Therapy in Patients with Advanced NSCLC
NSCLC IO 2022 - Midyear Review
Mechanisms of acquired resistance to anti–PD-(L)1 therapy in patients with advanced NSCLC are heterogeneous and require novel therapeutic strategies to be surmounted.
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Year in Review
Time-Dependent Efficacy of Nivolumab in Patients with Advanced NSCLC
NSCLC IO 2022 - Midyear Review
Administering nivolumab in the morning improved progression-free survival and overall survival compared with administration during later times of the day, suggesting that circadian rhythm may affect its efficacy.
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Year in Review
Impact of Performance Status on Response and Healthcare Utilization in Patients with Advanced NSCLC Treated with Immune Checkpoint Inhibitors
NSCLC IO 2022 - Midyear Review
Patients with NSCLC with poor performance status (PS) had significantly worse survival outcomes and were more likely to utilize healthcare services than those with favorable PS.
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Year in Review / Wrap-Ups
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