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Articles
Articles
Adjuvant Therapies in Major Histological Subtypes of Extremity Soft-Tissue Sarcoma (STS)
CTOS 2016
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Alternate Dosing Regimen of Regorafenib in Gastrointestinal Stromal Tumors (GISTs)
CTOS 2016
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Outcomes of Older Patients with Osteosarcoma from the French Group Sarcoma (GSF-GETO)
CTOS 2016
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Trabectedin Approved for Use in Uterine Leiomyosarcoma
CTOS 2016
In this interview, Martee Hensley, MD, a medical oncologist practicing at Memorial Sloan Kettering Cancer Center, commented on the introduction of trabectedin as a treatment alternative for women with uterine leiomyosarcoma.
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Phase 2 Trial Data on Metformin Do Not Support Further Investigation as a Breast Cancer Therapy
ESMO 2016
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Comparison of Sequential and Concomitant Adjuvant Trastuzumab Treatment in HER2+ Breast Cancer
ESMO 2016
The French SIGNAL and PHARE projects have collected data on more than 9800 patients with breast cancer since 2006. In evaluating the outcomes of sequential and concomitant administration of trastuzumab within this cohort, this study provides insight into the ideal administration protocol for patients with human epidermal growth factor receptor 2–positive (HER2+) breast cancer.
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Outcome Disparities by Prognostic Indicators in HR+ Breast Cancer
ESMO 2016
The 21-gene Recurrence Score® is the result of a commercial genomic test that evaluates the likelihood that breast cancer will recur, and the likely benefit from chemotherapy and/or radiation therapy. This study evaluates disparities in hormone receptor–positive (HR+) breast cancer outcome by age and 21-gene Recurrence Score®.
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Prognostic Role for Derived Neutrophil-to-Lymphocyte Ratio in Early Breast Cancer
ESMO 2016
Previous studies have reported that an elevated neutrophil-to-lymphocyte ratio is associated with an increased risk of relapse and worse survival in women with breast cancer. Additional data about the prognostic role for this biomarker in patients with early breast cancer are presented here.
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Interim Phase 2 Results on Abemaciclib in Women with HR+/HER2– Breast Cancer
ESMO 2016
In this ongoing phase 2 study, postmenopausal women with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER2–) breast cancer are being treated with abemaciclib (a selective inhibitor of cyclin-dependent kinases 4 and 6), anastrozole (an aromatase inhibitor), or both simultaneously.
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The FALCON Study: A Phase 3 Comparison of Fulvestrant and Anastrozole in ER+ Advanced Breast Cancer
ESMO 2016
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